Physicians envision a future in which genomic data from patients is heavily used to manage care—but experts have questioned the accuracy and reliability of these analyses. Now, a study by 150 researchers in 12 countries finds real strength and agreement across RNA genomic sequencing techniques and laboratories—as well as ways to improve what little variability exists to set a new high standard.
The results of the study were published in Nature Biotechnology in three separate research articles.
These results should provide assurance to patients, clinicians and the research community that genomic sequencing is accurate, says E. Aubrey Thompson, Ph.D., a professor of cancer biology at Mayo Clinic in Florida, one of three institutions that led the study. Dr. Thompson is a study co-author and member of the project leadership.